Hydrochloric Acid

Hydrochloric Acid

SCHEMBL960558

CCCC[n+]1ccn(CCC)c1.[Cl-]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.47
HSP90AA1 P07900 2/20 0.47
KMT2A Q03164 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
APAF1 O14727 1/20 0.44
NPC1 O15118 1/20 0.44
PLA2G1B P04054 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ATG4B Q9Y4P1 1/20 0.44
FDPS P14324 10/20 0.44
PON1 P27169 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL899120 0.98 MEN1 (0.49) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Iodide SCHEMBL1758472 0.96 MEN1 (0.47) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Bromide SCHEMBL3800998 0.96 MEN1 (0.51) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Hydrochloric Acid SCHEMBL960036 0.94 MEN1 (0.50) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Hydrochloric Acid SCHEMBL958506 0.93 MEN1 (0.53) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Hydrochloric Acid SCHEMBL11538568 0.93 MEN1 (0.53) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
SCHEMBL961671 0.92 MEN1 (0.51) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Hydrochloric Acid SCHEMBL558001 0.92 MEN1 (0.51) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
SCHEMBL28358357 0.91 MEN1 (0.44) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
SCHEMBL28349886 0.91 MEN1 (0.44) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9267214-B2 Aluminum recovery process BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2016-02-23 US claimed
US-20110000782-A1 ALUMINUM RECOVERY PROCESS THE UNIVERSITY OF ALABAMA (US) 2011-01-06 US claimed
WO-2009102419-A2 ALUMINUM RECOVERY PROCESS THE UNIVERSITY OF ALABAMA (US) 2009-08-20 WO claimed
EP-0404188-B1 Non-aqueous electrolytic aluminum plating bath composition NISSHIN STEEL CO LTD (JP) 1994-03-16 EP claimed
US-5074973-A Mixed melt containing aluminum halide, nitrogen-heterocyclic halides, additives, organic polymer NISSHIN STEEL CO. LTD. (JP) 1991-12-24 US claimed
EP-0404188-A1 Non-aqueous electrolytic aluminum plating bath composition NISSHIN STEEL CO., LTD. (JP) 1990-12-27 EP claimed
US-9267214-B2 Aluminum recovery process BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2016-02-23 US disclosed
US-20110000782-A1 ALUMINUM RECOVERY PROCESS THE UNIVERSITY OF ALABAMA (US) 2011-01-06 US disclosed
WO-2009131692-A1 SUBSTRATES FOR DELIVERY OF PHYSIOLOGICALLY ACTIVE AGENTS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2009-10-29 WO disclosed
WO-2009102419-A2 ALUMINUM RECOVERY PROCESS THE UNIVERSITY OF ALABAMA (US) 2009-08-20 WO disclosed
EP-0404188-A1 Non-aqueous electrolytic aluminum plating bath composition NISSHIN STEEL CO., LTD. (JP) 1990-12-27 EP disclosed