Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12011130 | 0.92 | PTGER4 (0.73) | PTGER4 | |
| SCHEMBL9606766 | 0.91 | PTGER4 (0.70) | PTGER4 | |
| SCHEMBL14431126 | 0.90 | PTGER4 (0.57) | PTGER4 | |
| SCHEMBL9606814 | 0.90 | PTGER4 (0.70) | PTGER4 | |
| SCHEMBL10058582 | 0.87 | PTGER4 (0.64) | PTGER4 | |
| SCHEMBL12011122 | 0.86 | PTGER4 (0.83) | PTGER4 | |
| SCHEMBL10058585 | 0.86 | PTGER4 (0.64) | PTGER4 | |
| SCHEMBL14430787 | 0.86 | PTGER4 (0.57) | PTGER4 | |
| SCHEMBL9606644 | 0.85 | PTGER4 (0.46) | PTGER4 | |
| SCHEMBL14431127 | 0.85 | PTGER4 (0.57) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979316-B1 | BENZO (F) ISOINDOL-2-YLPHENYL ACETIC ACID DERIVATIVES AS EP4 RECEPTOR AGONISTS | GLAXO GROUP LTD (GB) | 2012-07-11 | — | — | EP | disclosed |
| EP-2457897-A1 | BENZO (F) ISOINDOL-2-YLPHENYL ACETIC ACID DERIVATIVES AS EP4 RECEPTOR AGONISTS | Glaxo Group Limited (GB) | 2012-05-30 | — | — | EP | disclosed |