Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298754 | 0.90 | PTGER4 (0.86) | PTGER4 | |
| SCHEMBL9606633 | 0.90 | PTGER4 (0.62) | PTGER4 | |
| SCHEMBL10305433 | 0.88 | PTGER4 (0.83) | PTGER4 | |
| SCHEMBL14430838 | 0.87 | PTGER4 (0.65) | PTGER4 | |
| SCHEMBL13177220 | 0.85 | PTGER4 (0.70) | PTGER4 | |
| SCHEMBL1590569 | 0.85 | PTGER4 (0.75) | PTGER4 | |
| SCHEMBL1590668 | 0.84 | PTGER4 (0.75) | PTGER4 | |
| SCHEMBL2295490 | 0.83 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL12011130 | 0.82 | PTGER4 (0.73) | PTGER4 | |
| SCHEMBL12002068 | 0.82 | PTGER4 (0.65) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457897-A1 | BENZO (F) ISOINDOL-2-YLPHENYL ACETIC ACID DERIVATIVES AS EP4 RECEPTOR AGONISTS | Glaxo Group Limited (GB) | 2012-05-30 | — | — | EP | disclosed |