Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 8/20 | 0.47 |
| ▸ | MMP3 | P08254 | 6/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275085 | 1.00 | MAPT (0.51) | MAPTALDH1A1MMP2MMP3MMP1 | |
| SCHEMBL25501168 | 0.97 | MAPT (0.48) | MAPTALDH1A1MMP2MMP3MMP1 | |
| SCHEMBL26079395 | 0.97 | MAPT (0.48) | MAPTALDH1A1MMP2MMP3MMP1 | |
| SCHEMBL25501189 | 0.92 | MMP2 (0.44) | MAPTALDH1A1MMP2MMP3MMP1 | |
| SCHEMBL12032773 | 0.91 | MAPT (0.50) | MAPTALDH1A1MMP3SMN1; SMN2LMNA | |
| SCHEMBL13476114 | 0.90 | NPC1 (0.49) | MAPTALDH1A1SMN1; SMN2LMNAHDAC1 | |
| SCHEMBL14426022 | 0.89 | MAPT (0.46) | MAPTALDH1A1MMP2MMP3MMP1 | |
| SCHEMBL25802143 | 0.89 | RARB (0.51) | MAPTSMN1; SMN2LMNATP53HRH3 | |
| SCHEMBL25802116 | 0.89 | RARB (0.51) | MAPTSMN1; SMN2LMNATP53HRH3 | |
| SCHEMBL13987042 | 0.88 | MAPT (0.44) | MAPTALDH1A1MMP2MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120133882-A1 | LIQUID CRYSTAL FILM AND OPTICAL ELEMENT PRODUCED USING SAME | JX NIPPON OIL & ENERGY CORPORATION (JP) | 2012-05-31 | — | — | US | disclosed |