SCHEMBL9608413

SCHEMBL9608413

COC(=O)c1ccc(-c2nc(-c3ccccc3O)nc(-c3ccc(Oc4ccccc4)cc3O)n2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.52
MAPT P10636 7/20 0.51
NPSR1 Q6W5P4 5/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
POLB P06746 1/20 0.51
ALDH1A1 P00352 5/20 0.48
GAA P10253 2/20 0.48
KDM4A O75164 1/20 0.47
TSHR P16473 4/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
HPGD P15428 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
GLA P06280 1/20 0.45
ALOX15 P16050 2/20 0.44
RAB9A P51151 2/20 0.44
ADORA3 P0DMS8 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA2B P29275 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12228446 0.95 EGFR (0.57) EGFRMAPTNPSR1MEN1KMT2A
SCHEMBL9608448 0.94 MAPT (0.50) EGFRMAPTNPSR1MEN1KMT2A
SCHEMBL12228408 0.92 EGFR (0.53) EGFRMAPTNPSR1MEN1KMT2A
SCHEMBL12228456 0.90 EGFR (0.53) EGFRMAPTNPSR1MEN1KMT2A
SCHEMBL9609244 0.90 MEN1 (0.54) EGFRMAPTNPSR1MEN1KMT2A
SCHEMBL9608528 0.89 MAPT (0.50) EGFRMAPTNPSR1MEN1KMT2A
SCHEMBL12755015 0.89 EGFR (0.52) EGFRMAPTNPSR1MEN1KMT2A
SCHEMBL9608434 0.87 MAPT (0.58) EGFRMAPTNPSR1MEN1KMT2A
SCHEMBL12228440 0.87 EGFR (0.59) EGFRMAPTNPSR1MEN1KMT2A
SCHEMBL9608388 0.87 MAPT (0.60) EGFRMAPTNPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160200933-A1 RESIN COMPOSITION, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed
US-20160200933-A1 RESIN COMPOSITION, PROTECTIVE FILM FOR POLARIZING PLATE, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 EGFR 4291/4885MAPT 1774/4885NPSR1 937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.