SCHEMBL9608481

SCHEMBL9608481

Cc1ccc(-c2nc(-c3ccc(C(=O)OCC(CCC(C)CCCC(C)C)C(C)CCCC(C)C)cc3)nc(-c3ccccc3O)n2)c(O)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.39
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
ALOX15 P16050 3/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPSR1 Q6W5P4 2/20 0.35
POLB P06746 1/20 0.35
TSHR P16473 3/20 0.34
NPC1 O15118 2/20 0.34
LMNA P02545 2/20 0.34
PLA2G1B P04054 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4A O75164 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12755010 0.96 NPC1 (0.35) MAPTKMT2AMEN1ALOX15HPGD
SCHEMBL9608410 0.94 MAPT (0.39) MAPTKMT2AMEN1ALOX15HPGD
SCHEMBL9609314 0.90 MAPT (0.36) MAPTKMT2AMEN1ALOX15HPGD
SCHEMBL9608509 0.86 ADORA2A (0.40) MAPTKMT2AMEN1ALOX15HPGD
SCHEMBL12228406 0.86 MEN1 (0.37) MAPTKMT2AMEN1ALOX15HPGD
SCHEMBL9608479 0.85 KMT2A (0.39) MAPTKMT2AMEN1ALOX15HPGD
SCHEMBL9608476 0.84 MAPT (0.41) MAPTKMT2AMEN1ALOX15HPGD
SCHEMBL9608478 0.82 MAPT (0.41) MAPTKMT2AMEN1ALOX15HPGD
SCHEMBL17917589 0.82 ADORA2A (0.36) MAPTKMT2AMEN1ALOX15HPGD
SCHEMBL9608486 0.82 KMT2A (0.41) MAPTKMT2AMEN1ALOX15HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8957140-B2 Triazine derivative, ultraviolet absorber, and resin composition FUJIFILM CORPORATION (JP) 2015-02-17 US disclosed
US-8748520-B2 Polycarbonate resin composition containing triazine compound and molded article using the same FUJIFILM CORPORATION (JP) 2014-06-10 US disclosed
US-8623990-B2 Polyester resin composition FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-20120301696-A1 POLYESTER RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-11-29 US disclosed
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2012-05-31 US disclosed
US-20110077331-A1 POLYCARBONATE RESIN COMPOSITION CONTAINING TRIAZINE COMPOUND AND MOLDED ARTICLE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136098-A1 NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION C1R, RPSA, H1-2 MAPT 1774/4885KMT2A 1270/4885MEN1 2282/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.