Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.80 |
| ▸ | CA1 | P00915 | 1/20 | 0.80 |
| ▸ | CA2 | P00918 | 1/20 | 0.80 |
| ▸ | CA3 | P07451 | 1/20 | 0.80 |
| ▸ | CA4 | P22748 | 1/20 | 0.80 |
| ▸ | CA6 | P23280 | 1/20 | 0.80 |
| ▸ | CA5A | P35218 | 1/20 | 0.80 |
| ▸ | CA7 | P43166 | 1/20 | 0.80 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.80 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.80 |
| ▸ | CA9 | Q16790 | 1/20 | 0.80 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.80 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.80 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.80 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ANPEP | P15144 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lacosamide SCHEMBL35330 | 0.89 | CA12 (1.00) | CA12CA1CA2CA3CA4 | |
| Lacosamide SCHEMBL223961 | 0.89 | CA12 (1.00) | CA12CA1CA2CA3CA4 | |
| Lacosamide SCHEMBL225889 | 0.89 | CA12 (1.00) | CA12CA1CA2CA3CA4 | |
| Lacosamide SCHEMBL28184085 | 0.87 | CA12 (0.97) | CA12CA1CA2CA3CA4 | |
| SCHEMBL527808 | 0.87 | CA12 (0.81) | CA12CA1CA2CA3CA4 | |
| SCHEMBL14931211 | 0.87 | CA12 (0.81) | CA12CA1CA2CA3CA4 | |
| SCHEMBL8601669 | 0.86 | CA12 (0.94) | CA12CA1CA2CA3CA4 | |
| SCHEMBL18080796 | 0.84 | CA12 (0.77) | CA12CA1CA2CA3CA4 | |
| SCHEMBL10070442 | 0.84 | CA12 (0.68) | CA12CA1CA2CA3CA4 | |
| SCHEMBL2319131 | 0.83 | CA12 (0.75) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069855-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | CAMBREX KARLSKOGA AB (SE) | 2012-05-31 | — | — | WO | disclosed |