Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13573704 | 0.84 | DPP4 (0.55) | DPP4CYP3A4CYP2C9CYP2C19TAS1R3 | |
| SCHEMBL13573038 | 0.84 | DPP4 (0.55) | DPP4CYP3A4CYP2C9CYP2C19TAS1R3 | |
| SCHEMBL10453345 | 0.81 | DPP4 (0.50) | DPP4ALDH1A1DPP8DPP7POLB | |
| SCHEMBL9891896 | 0.80 | CYP3A4 (0.44) | DPP4CYP3A4CYP2C9CYP2C19TAS1R3 | |
| SCHEMBL21789475 | 0.80 | CYP3A4 (0.44) | DPP4CYP3A4CYP2C9CYP2C19TAS1R3 | |
| SCHEMBL25927227 | 0.80 | CYP3A4 (0.44) | DPP4CYP3A4CYP2C9CYP2C19TAS1R3 | |
| SCHEMBL19882791 | 0.79 | DPP4 (0.48) | DPP4DPP8DPP7PAX8FAP | |
| SCHEMBL944394 | 0.77 | CYP3A4 (0.45) | DPP4CYP3A4CYP2C9CYP2C19TAS1R3 | |
| SCHEMBL13035837 | 0.77 | CYP3A4 (0.45) | DPP4CYP3A4CYP2C9CYP2C19TAS1R3 | |
| SCHEMBL13036625 | 0.77 | CYP3A4 (0.45) | DPP4CYP3A4CYP2C9CYP2C19TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457896-A1 | Tripeptides as caspase modulators | Idun Pharmaceuticals, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |