Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21789475 | 1.00 | CYP3A4 (0.44) | CYP3A4CYP2C9CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL13036625 | 0.81 | CYP3A4 (0.45) | CYP3A4CYP2C9CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL944394 | 0.81 | CYP3A4 (0.45) | CYP3A4CYP2C9CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL13035837 | 0.81 | CYP3A4 (0.45) | CYP3A4CYP2C9CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL9608873 | 0.80 | DPP4 (0.50) | CYP3A4CYP2C9CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL12084428 | 0.79 | DPP4 (0.36) | CYP3A4CYP2C9CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL12556297 | 0.78 | CYP3A4 (0.40) | CYP3A4CYP2C9CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL15705342 | 0.78 | CYP3A4 (0.40) | CYP3A4CYP2C9CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL13573704 | 0.78 | DPP4 (0.55) | CYP3A4CYP2C9CYP2C19TAS1R3TAS1R1 | |
| SCHEMBL13573038 | 0.78 | DPP4 (0.55) | CYP3A4CYP2C9CYP2C19TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | CYP3A4 1707/4885CYP2C9 1894/4885CYP2C19 1646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.