Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28577614 | 0.94 | ALDH1A1 (0.50) | ALDH1A1TDP1SMN1; SMN2TP53CYP1A2 | |
| SCHEMBL426021 | 0.88 | ALDH1A1 (0.56) | ALDH1A1TDP1SMN1; SMN2TP53CYP1A2 | |
| SCHEMBL15803233 | 0.84 | ALDH1A1 (0.51) | ALDH1A1TDP1SMN1; SMN2TP53CYP1A2 | |
| SCHEMBL419966 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TDP1SMN1; SMN2TP53MEN1 | |
| SCHEMBL9609237 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TDP1SMN1; SMN2TP53CYP1A2 | |
| SCHEMBL9609207 | 0.79 | HSD17B10 (0.45) | ALDH1A1TDP1SMN1; SMN2TP53CYP1A2 | |
| SCHEMBL13198026 | 0.79 | CYP3A4 (0.49) | ALDH1A1TDP1SMN1; SMN2TP53CYP1A2 | |
| SCHEMBL13206982 | 0.78 | TDP1 (0.44) | ALDH1A1TDP1SMN1; SMN2TP53CYP1A2 | |
| SCHEMBL9609209 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TDP1SMN1; SMN2TP53CYP1A2 | |
| SCHEMBL14859939 | 0.77 | ALDH1A1 (0.51) | ALDH1A1TDP1SMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9551029-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2017-01-24 | — | — | US | disclosed |
| US-20160122813-A1 | Methods And Kits Using Extended Rhodamine Dyes | THE PERKIN-ELMER CORPORATION | 2016-05-05 | — | — | US | disclosed |
| US-9309561-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2016-04-12 | — | — | US | disclosed |
| US-20140171336-A1 | Methods and Kits Using Extended Rhodamine Dyes | Life Technologies Corporation (US) | 2014-06-19 | — | — | US | disclosed |
| US-8628975-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2014-01-14 | — | — | US | disclosed |
| US-20120135885-A1 | Methods and Kits Using Extended Rhodamine Dyes | Life Technologies Corporation (US) | 2012-05-31 | — | — | US | disclosed |
| US-8124746-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110053282-A1 | Methods and Kits Using Extended Rhodamine Dyes | Life Technologies Corporation (US) | 2011-03-03 | — | — | US | disclosed |
| US-7776568-B2 | Rhodamine dye compounds for patterns with DNA sequences for kits | APPLIED BIOSYSTEMS, LLC (US) | 2010-08-17 | — | — | US | disclosed |
| US-7776568-B2 | Rhodamine dye compounds for patterns with DNA sequences for kits | APPLIED BIOSYSTEMS, LLC (US) | 2010-08-17 | — | — | US | disclosed |