SCHEMBL9609728

SCHEMBL9609728

CCO[Si](CCCNC(=O)NCc1ccc2ccccc2c1)(OCC)OCC

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.50
NAMPT P43490 1/20 0.46
BCHE P06276 1/20 0.45
ACHE P22303 1/20 0.45
EPHX1 P07099 1/20 0.44
IDO1 P14902 1/20 0.43
EPHX2 P34913 1/20 0.43
FAAH O00519 1/20 0.41
HDAC3 O15379 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC8 Q9BY41 1/20 0.41
MC4R P32245 1/20 0.41
MC5R P33032 1/20 0.41
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
KMT2A Q03164 1/20 0.40
CASR P41180 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13567340 0.86 EPHX2 (0.48) EPHX1EPHX2FAAHALDH1A1
SCHEMBL9609725 0.84 MC5R (0.57) BCHEACHEIDO1HDAC3HDAC1
SCHEMBL9609731 0.82 TGM2 (0.47) CNR2BCHEACHEFAAHHDAC3
SCHEMBL6270335 0.82 EPHX1 (0.67) CNR2EPHX1KDM4EMEN1ALDH1A1
SCHEMBL9609709 0.80 NPC1 (0.41) EPHX2FAAHKDM4EMEN1ALDH1A1
SCHEMBL10312316 0.79 EPHX1 (0.62) CNR2EPHX1ALDH1A1KMT2A
SCHEMBL15746415 0.78 EPHX2 (0.49) EPHX2HDAC3HDAC8MEN1KMT2A
SCHEMBL485762 0.77 EPHX1 (0.55) EPHX1EPHX2HDAC3HDAC1HDAC2
SCHEMBL6277478 0.76 EPHX1 (0.44) CNR2EPHX1MEN1ALDH1A1KMT2A
SCHEMBL9609701 0.76 MC5R (0.45) BCHEACHEHDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8921243-B2 Fabrics comprising a photocatalyst to produce singlet oxygen from ambient oxygen VENTANA RESEARCH CORPORATION 2014-12-30 US disclosed
US-8481446-B2 Chemically-resistant coating composition VENTANA RESEARCH CORPORATION 2013-07-09 US disclosed
US-8481446-B2 Chemically-resistant coating composition VENTANA RESEARCH CORPORATION 2013-07-09 US disclosed
US-20120135651-A1 Fabrics Comprising a Photocatalyst to Produce Singlet Oxygen from Ambient Oxygen VENTANA RESEARCH CORPORATION 2012-05-31 US disclosed
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION VENTANA RESEARCH CORPORATION 2010-11-04 US disclosed
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION VENTANA RESEARCH CORPORATION 2010-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279850-A1 CHEMICALLY-RESISTANT COATING COMPOSITION DNMT1, VCL, DNMT3L CNR2 1620/4885NAMPT 3056/4885BCHE 3469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.