Methylene Chloride

Methylene Chloride

SCHEMBL961114

COC(=O)CCCCCO.ClCCl

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
LMNA P02545 2/20 0.52
ALDH1A1 P00352 1/20 0.52
GPR84 Q9NQS5 1/20 0.44
FFAR1 O14842 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
KMT2A Q03164 1/20 0.43
KDM4E B2RXH2 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
RECQL P46063 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
KAT2B Q92831 1/20 0.41
EPHX2 P34913 2/20 0.40
GAA P10253 1/20 0.40
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39
HPGD P15428 1/20 0.39
POLB P06746 1/20 0.39
POLA1 P09884 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4758137 0.93 TSHR (0.67) TSHRLMNAALDH1A1GPR84FFAR1
SCHEMBL1886420 0.93 TSHR (0.67) TSHRLMNAALDH1A1GPR84FFAR1
SCHEMBL4757158 0.93 TSHR (0.67) TSHRLMNAALDH1A1GPR84FFAR1
SCHEMBL2235775 0.93 TSHR (0.67) TSHRLMNAALDH1A1GPR84FFAR1
SCHEMBL1976107 0.93 TSHR (0.67) TSHRLMNAALDH1A1GPR84FFAR1
SCHEMBL816422 0.93 TSHR (0.67) TSHRLMNAALDH1A1GPR84FFAR1
SCHEMBL1245383 0.93 TSHR (0.67) TSHRLMNAALDH1A1GPR84FFAR1
SCHEMBL1277943 0.93 TSHR (0.67) TSHRLMNAALDH1A1GPR84FFAR1
SCHEMBL1199597 0.93 TSHR (0.67) TSHRLMNAALDH1A1GPR84FFAR1
SCHEMBL4758469 0.93 TSHR (0.67) TSHRLMNAALDH1A1GPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8497003-B2 Glucose compound, cellulose composition, cellulose film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2013-07-30 US disclosed
EP-1773572-B1 METHOD OF MANUFACTURING A THERMOPLASTIC FILM, THERMOPLASTIC FILM AND ITS USE FUJIFILM CORP (JP) 2013-06-26 EP disclosed
US-8308862-B2 Replacement of hydroxyl group of cellulose with acrylic acid or acetic acid groups FUJIFILM CORPORATION (JP) 2012-11-13 US disclosed
US-8304040-B2 cellulose esters used as birefringence and protective coatings for polarizing and optical filters in liquid crystal displays FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-8233116-B2 Polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-07-31 US disclosed
US-8227053-B2 Optically compensatory film, polarizing plate and liquid-crystal display FUJIFILM CORPORATION (JP) 2012-07-24 US disclosed
US-8085365-B2 Cellulose acylate film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-12-27 US disclosed
US-8043714-B2 Transparent thermoplastic film and a method of producing the same FUJIFILM CORPORATION (JP) 2011-10-25 US disclosed
US-20110242460-A1 CELLULOSE ACYLATE FILM AND METHOD FOR MANUFACTURING THE SAME, RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-10-06 US disclosed
US-7951430-B2 Cellulose acylate film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-05-31 US disclosed
US-20060004192-A1 Method of preparing a cellulose acylate, cellulose acylate film, polarizing plate, and liquid crystal display device FUJI PHOTO FILM CO., LTD. 2006-01-05 US disclosed
WO-2005114272-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2005-12-01 WO disclosed
WO-2005111124-A1 OPTICAL CELLULOSE ACYLATE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2005-11-24 WO disclosed
US-20050234231-A1 Cellulose acylate film and method for producing the same FUJI PHOTO FILM CO., LTD. (JP) 2005-10-20 US disclosed
WO-2005080482-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJI PHOTO FILM CO., LTD. (JP) 2005-09-01 WO disclosed
US-20050186360-A1 Cellulose acylate film FUJI FILM PHOTO CO., LTD. (JP) 2005-08-25 US disclosed
US-20050163923-A1 Polymer film and preparation method of polymer solution FUJI PHOTO FILM CO. LTD. (JP) 2005-07-28 US disclosed
WO-2005064369-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJI PHOTO FILM CO., LTD. (JP) 2005-07-14 WO disclosed
US-20050142304-A1 Optical cellulose acylate film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2005-06-30 US disclosed
US-20040247918-A1 Cellulose acylate-based dope, cellulose acylate film, and method of producing a cellulose acylate film FUJI PHOTO FILM CO., LTD. (JP) 2004-12-09 US disclosed