Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758469 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1GPR84FFAR1 | |
| SCHEMBL4757158 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1GPR84FFAR1 | |
| SCHEMBL1277943 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1GPR84FFAR1 | |
| SCHEMBL4758137 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1GPR84FFAR1 | |
| SCHEMBL1199597 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1GPR84FFAR1 | |
| SCHEMBL1976107 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1GPR84FFAR1 | |
| SCHEMBL1886420 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1GPR84FFAR1 | |
| SCHEMBL1245383 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1GPR84FFAR1 | |
| SCHEMBL2235775 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1GPR84FFAR1 | |
| SCHEMBL4758409 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180002729-A1 | METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUNDS | INVISTA NORTH AMERICA S.A.R.L. | 2018-01-04 | — | — | US | claimed |
| CN-106795537-A | Methods, reagents and cells for biosynthesis of compounds | 英威达技术有限责任公司 | 2017-05-31 | — | — | CN | claimed |
| EP-3155109-A1 | METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUNDS | Invista Technologies S.A R.L. (CH) | 2017-04-19 | — | — | EP | claimed |
| WO-2015195678-A1 | METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUNDS | INVISTA TECHNOLOGIES S.À R.L. (CH) | 2015-12-23 | — | — | WO | claimed |
| US-20150361465-A1 | METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUNDS | INV NYLON CHEMICALS AMERICAS, LLC | 2015-12-17 | — | — | US | claimed |
| EP-4727537-A2 | SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF | Adaxion Therapeutics, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20250064941-A1 | SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF | ADAXION THERAPEUTICS, INC. | 2025-02-27 | — | — | US | disclosed |
| WO-2024259007-A2 | SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF | OSPREY BIOPHARMACEUTICALS, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| CN-115141123-B | Compound, preparation method thereof and application thereof in preparation of dual inhibitors of histone deacetylase and epoxide hydrolase | 沈阳药科大学 | 2024-05-17 | — | — | CN | disclosed |
| CN-117865991-A | Preparation and application of biotin-coupled dihydroartemisinin | 成都理工大学 | 2024-04-12 | — | — | CN | disclosed |
| CN-113387938-B | Substituted pyrimidine compound, preparation method, intermediate and application thereof | 上海科技大学 | 2023-08-18 | — | — | CN | disclosed |
| CN-110959009-B | Method for introducing substituent to alpha, beta-unsaturated ketone and method for synthesizing prostanoid using the same | 国立研究开发法人国立长寿医疗研究中心 | 2023-02-28 | — | — | CN | disclosed |
| WO-1997001543-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |
| US-5457205-A | Substituted thiazoles useful for treatment of diabetes | DR. KARL THOMAE GMBH (DE) | 1995-10-10 | — | — | US | disclosed |
| US-RE34722-E | Antiulcer agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| US-5219852-A | Hypoglycemic agents, treatment of diabetes and obesity | DR. KARL THOMAE GMBH (DE) | 1993-06-15 | — | — | US | disclosed |
| US-5026702-A | Enhances physical performance in animals, effective in lowering blood sugar, reducing body fat and lowering atherogenic lipoproteins | DR. KARL THOMAE, GMBH (DE) | 1991-06-25 | — | — | US | disclosed |
| US-4886814-A | LOWER BLOOD SUGAR | DR. KARL THOMAS GMBH (DE) | 1989-12-12 | — | — | US | disclosed |
| US-4859799-A | Process for the production of aldehyde or ketone compounds and aldehydes and ketones obtained by means of this process | INTEROX (SOCIETE ANONYME) (BE) | 1989-08-22 | — | — | US | disclosed |
| US-4578381-A | ANTIULCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150361465-A1 | METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUNDS | PNMT, HNMT, ACOT7 | TSHR 2112/4885LMNA 3733/4885ALDH1A1 302/4885 |
| US-20250064941-A1 | SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF | SIGLEC7, SIGLEC9, CD2BP2 | TSHR 1160/4885LMNA 2421/4885ALDH1A1 802/4885 |
| US-20180002729-A1 | METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUNDS | PNMT, HNMT, ACOT7 | TSHR 2112/4885LMNA 3733/4885ALDH1A1 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.