Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9611963 | 0.91 | — | — | |
| SCHEMBL17243598 | 0.85 | — | — | |
| SCHEMBL9611961 | 0.82 | — | — | |
| SCHEMBL19680373 | 0.78 | — | — | |
| SCHEMBL804365 | 0.76 | MEN1 (0.38) | CYP3A4TSHR | |
| SCHEMBL8736107 | 0.74 | SMN1; SMN2 (0.37) | CYP3A4 | |
| SCHEMBL804728 | 0.74 | TSHR (0.38) | CYP3A4TSHR | |
| SCHEMBL15702195 | 0.73 | THRB (0.39) | TSHR | |
| SCHEMBL10331167 | 0.73 | TSHR (0.38) | CYP3A4TSHR | |
| SCHEMBL12937852 | 0.72 | MEN1 (0.38) | CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181401-B2 | Phosphorylcholine-based amphiphilic silicones for medical applications | DSM IP ASSETS B.V. (NL) | 2015-11-10 | — | — | US | disclosed |
| US-20120136087-A1 | PHOSPHORYLCHOLINE-BASED AMPHIPHILIC SILICONES FOR MEDICAL APPLICATIONS | DSM IP ASSETS B.V. (NL) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136087-A1 | PHOSPHORYLCHOLINE-BASED AMPHIPHILIC SILICONES FOR MEDICAL APPLICATIONS | PHOSPHO1, SGMS1, PLA2G2C | CYP3A4 4833/4885TSHR 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.