Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 18/20 | 0.66 |
| ▸ | SLC5A1 | P13866 | 10/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | SLC5A11 | Q8WWX8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12285346 | 1.00 | SLC5A2 (0.66) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL17189182 | 1.00 | SLC5A2 (0.66) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL12801854 | 1.00 | SLC5A2 (0.66) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL12285244 | 0.94 | SLC5A2 (0.66) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL19620341 | 0.93 | SLC5A2 (0.69) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL18264983 | 0.91 | SLC5A2 (0.65) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL18573896 | 0.91 | SLC5A2 (0.60) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL12285351 | 0.90 | SLC5A2 (0.61) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL1038483 | 0.90 | SLC5A2 (0.61) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL3628095 | 0.90 | SLC5A2 (0.59) | SLC5A2SLC5A1ADRA2ASLC5A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457918-A2 | Crystalline solvates and complexes of (1s)-1,5-anhydro-1-c-(3-((phenyl) methyl) phenyl)-d-glucitol derivatives with amino acids as SGLT2 inhibitors for the treatment of diabetes | Bristol-Myers Squibb Company (US) | 2012-05-30 | — | — | EP | disclosed |
| WO-2008002824-A1 | CRYSTALLINE SOLVATES AND COMPLEXES OF (IS) -1, 5-ANHYDRO-L-C- (3- ( (PHENYL) METHYL) PHENYL) -D-GLUCITOL DERIVATIVES WITH AMINO ACIDS AS SGLT2 INHIBITORS FOR THE TREATMENT OF DIABETES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-01-03 | — | — | WO | disclosed |