SCHEMBL3628095

SCHEMBL3628095

CCOc1ccc(Cc2cc([C@@H]3OC(S)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]3OC(C)=O)ccc2Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 18/20 0.59
SLC5A1 P13866 9/20 0.58
ADRA2A P08913 1/20 0.56
SLC5A11 Q8WWX8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12285810 1.00 SLC5A2 (0.59) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL12285346 0.90 SLC5A2 (0.66) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL9611976 0.90 SLC5A2 (0.66) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL17189182 0.90 SLC5A2 (0.66) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL12285351 0.90 SLC5A2 (0.61) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL12801854 0.90 SLC5A2 (0.66) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL1038483 0.90 SLC5A2 (0.61) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL1038646 0.90 SLC5A2 (0.67) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL1038645 0.90 SLC5A2 (0.58) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18265370 0.90 SLC5A2 (0.68) SLC5A2SLC5A1ADRA2ASLC5A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120095197-A1 METHODS AND COMPOUNDS USEFUL FOR THE PREPARATION OF SODIUM GLUCOSE CO-TRANSPORTER 2 INHIBITORS OXFORD FINANCE LLC, AS COLLATERAL AGENT 2012-04-19 US disclosed
EP-2183263-B1 METHODS AND COMPOUNDS USEFUL FOR THE PREPARATION OF SODIUM GLUCOSE CO-TRANSPORTER 2 INHIBITORS LEXICON PHARMACEUTICALS INC (US) 2011-10-26 EP disclosed
WO-2009014970-A1 METHODS AND COMPOUNDS USEFUL FOR THE PREPARATION OF SODIUM GLUCOSE CO-TRANSPORTER 2 INHIBITORS LEXICON PHARMACEUTICALS, INC. (US) 2009-01-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120095197-A1 METHODS AND COMPOUNDS USEFUL FOR THE PREPARATION OF SODIUM GLUCOSE CO-TRANSPORTER 2 INHIBITORS SLC2A2, SLC2A1, SLC5A2 SLC5A2 3/4885SLC5A1 8/4885ADRA2A 1593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.