SCHEMBL9612008

SCHEMBL9612008

Cc1ccccc1N1C(=O)C(=O)N(c2ccccc2C)C1=S

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.59
KMT2A Q03164 5/20 0.53
MEN1 O00255 3/20 0.53
MAPT P10636 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.50
ELANE P08246 1/20 0.50
CASP3 P42574 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
CASP6 P55212 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.45
LMNA P02545 2/20 0.44
GAA P10253 1/20 0.44
ALDH1A1 P00352 3/20 0.44
POLB P06746 2/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29379598 0.77 KMT2A (0.73) MGLLKMT2AMEN1MAPTELANE
SCHEMBL30758615 0.77 KMT2A (0.73) MGLLKMT2AMEN1MAPTELANE
SCHEMBL30777592 0.77 KMT2A (0.73) MGLLKMT2AMEN1MAPTELANE
SCHEMBL2550815 0.77 KMT2A (0.73) MGLLKMT2AMEN1MAPTELANE
SCHEMBL10983420 0.74 MGLL (0.62) MGLLKMT2AMEN1MAPTSMN1; SMN2
SCHEMBL137793 0.74 MGLL (1.00) MGLLKMT2AMEN1MAPTSMN1; SMN2
SCHEMBL29366282 0.74 MGLL (1.00) MGLLKMT2AMEN1MAPTSMN1; SMN2
SCHEMBL13848408 0.74 MAPT (0.55) MGLLKMT2AMEN1MAPTSMN1; SMN2
SCHEMBL13084694 0.73 KMT2A (0.74) MGLLKMT2AMEN1MAPTELANE
SCHEMBL28460775 0.73 KMT2A (0.64) MGLLKMT2AMEN1MAPTELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2643416-B1 THE USE OF ARYL OR HETEROARYL SUBSTITUTED DITHIOLENE METAL COMPLEXES AS IR ABSORBERS BASF SE (DE) 2019-08-07 EP disclosed
US-20130234427-A1 THE USE OF ARYL OR HETEROARYL SUBSTITUTED DITHIOLENE METAL COMPLEXES AS IR ABSORBERS BASF SE (DE) 2013-09-12 US disclosed
US-20130234427-A1 THE USE OF ARYL OR HETEROARYL SUBSTITUTED DITHIOLENE METAL COMPLEXES AS IR ABSORBERS BASF SE (DE) 2013-09-12 US disclosed
WO-2012069518-A1 THE USE OF ARYL OR HETEROARYL SUBSTITUTED DITHIOLENE METAL COMPLEXES AS IR ABSORBERS BASF SE (DE) 2012-05-31 WO disclosed