Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28005234 | 0.88 | ALDH1A1 (0.36) | — | |
| SCHEMBL3000291 | 0.83 | KDM4E (0.42) | KDM4EL3MBTL1CYP1A2CYP3A4HPGD | |
| SCHEMBL12560663 | 0.79 | MAPK1 (0.48) | KDM4EL3MBTL1CYP1A2CYP3A4HPGD | |
| SCHEMBL4827207 | 0.77 | ALDH1A1 (0.50) | KDM4EL3MBTL1CYP1A2CYP3A4HPGD | |
| SCHEMBL12560730 | 0.77 | MAPK1 (0.50) | KDM4EL3MBTL1CYP1A2CYP3A4HPGD | |
| SCHEMBL29603166 | 0.77 | MAPK1 (0.50) | KDM4EL3MBTL1CYP1A2CYP3A4HPGD | |
| SCHEMBL1534946 | 0.77 | MAPK1 (0.50) | KDM4EL3MBTL1CYP1A2CYP3A4HPGD | |
| SCHEMBL24337390 | 0.77 | ALDH1A1 (0.38) | MAPK1TDP1 | |
| SCHEMBL30396122 | 0.77 | MAPK1 (0.50) | KDM4EL3MBTL1CYP1A2CYP3A4HPGD | |
| SCHEMBL295397 | 0.77 | MAPK1 (0.50) | KDM4EL3MBTL1CYP1A2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2148909-B1 | BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-30 | — | — | EP | disclosed |