SCHEMBL9612927

SCHEMBL9612927

Cc1ccncc1-c1ccc(-c2c3ccccc3c(-c3cccc4ccccc34)c3ccccc23)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.50
CYP17A1 P05093 6/20 0.49
CYP1A2 P05177 4/20 0.49
TNF P01375 2/20 0.48
CYP11B1 P15538 2/20 0.42
CYP11B2 P19099 2/20 0.42
ENPP3 O14638 1/20 0.42
ENPP1 P22413 1/20 0.42
SLC22A12 Q96S37 1/20 0.41
DHFR P00374 1/20 0.40
PRKCZ Q05513 1/20 0.40
ABL1 P00519 1/20 0.40
MAPK11 Q15759 1/20 0.40
MAPK14 Q16539 1/20 0.40
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9612963 0.90 CYP17A1 (0.50) DHODHCYP17A1CYP1A2TNFCYP11B1
SCHEMBL18174671 0.90 TNF (0.47) DHODHCYP17A1CYP1A2TNFCYP11B1
SCHEMBL9612899 0.89 CYP17A1 (0.47) DHODHCYP17A1CYP1A2TNFCYP11B1
SCHEMBL9612833 0.89 CYP17A1 (0.49) DHODHCYP17A1CYP1A2TNFCYP11B1
SCHEMBL9612933 0.89 TNF (0.48) DHODHCYP17A1CYP1A2TNFENPP3
SCHEMBL18174554 0.88 DHODH (0.52) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL18174788 0.87 DHODH (0.50) DHODHCYP17A1CYP1A2CYP11B1CYP11B2
SCHEMBL18174770 0.86 DHODH (0.49) DHODHCYP17A1CYP1A2TNFCYP11B1
SCHEMBL9612942 0.86 DHODH (0.52) DHODHCYP17A1CYP1A2TNFCYP11B1
SCHEMBL9612957 0.84 DHODH (0.48) DHODHCYP17A1CYP1A2CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012070535-A1 ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME JNC株式会社 (JP) 2012-05-31 WO disclosed