SCHEMBL9612932

SCHEMBL9612932

c1cncc(-c2ccc(-c3c4ccccc4c(-c4cccc5ccccc45)c4ccccc34)cc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
KDM4E B2RXH2 2/20 0.55
MAPT P10636 2/20 0.55
HPGD P15428 2/20 0.55
RAB9A P51151 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
CYP11B1 P15538 2/20 0.50
CYP19A1 P11511 2/20 0.49
CYP11B2 P19099 2/20 0.49
CYP17A1 P05093 1/20 0.49
TNF P01375 1/20 0.47
CYP2A6 P11509 4/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
DHODH Q02127 2/20 0.45
BCHE P06276 1/20 0.44
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43
HTT P42858 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14461162 0.92 ALDH1A1 (0.58) ALDH1A1KDM4EMAPTHPGDRAB9A
SCHEMBL17320843 0.92 CYP11B1 (0.55) ALDH1A1KDM4EMAPTHPGDRAB9A
SCHEMBL17320842 0.92 CYP11B1 (0.55) ALDH1A1KDM4EMAPTHPGDRAB9A
SCHEMBL24345162 0.91 MAPT (0.47) ALDH1A1KDM4EMAPTHPGDRAB9A
SCHEMBL15158447 0.91 ALDH1A1 (0.47) ALDH1A1KDM4EMAPTHPGDRAB9A
SCHEMBL17320743 0.91 CYP11B1 (0.49) ALDH1A1KDM4EMAPTHPGDRAB9A
SCHEMBL15977925 0.90 CYP11B1 (0.53) ALDH1A1KDM4EMAPTHPGDRAB9A
SCHEMBL14463294 0.90 ALDH1A1 (0.46) ALDH1A1KDM4EMAPTHPGDRAB9A
SCHEMBL15158443 0.90 ALDH1A1 (0.46) ALDH1A1KDM4EMAPTHPGDRAB9A
SCHEMBL15158448 0.90 ALDH1A1 (0.46) ALDH1A1KDM4EMAPTHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012070535-A1 ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME JNC株式会社 (JP) 2012-05-31 WO disclosed