SCHEMBL9612971

SCHEMBL9612971

Cc1cccc2c(-c3c4ccccc4c(-c4ccc(-c5ccnc(-c6ccc7ccccc7c6)c5)cc4)c4ccccc34)cccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPKAPK2 P49137 1/20 0.40
HTR2B P41595 1/20 0.37
HTR5A P47898 1/20 0.37
PIM1 P11309 1/20 0.37
SIRT2 Q8IXJ6 3/20 0.36
MAPT P10636 2/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP1A2 P05177 3/20 0.35
NPC1 O15118 2/20 0.35
AR P10275 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HPGD P15428 2/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
KDM4E B2RXH2 1/20 0.35
NFKB1 P19838 1/20 0.35
GFER P55789 1/20 0.35
NFKB2 Q00653 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9612973 0.94 MAPKAPK2 (0.41) MAPKAPK2HTR2BHTR5ASIRT2MAPT
SCHEMBL9612975 0.90 PIM1 (0.44) MAPKAPK2HTR2BHTR5APIM1SIRT2
SCHEMBL9613011 0.88 CA12 (0.39) ALDH1A1CYP1A2HPGDMEN1KMT2A
SCHEMBL10017223 0.82 MAPK9 (0.43) MAPKAPK2HTR2BHTR5APIM1SIRT2
SCHEMBL9612990 0.82 MAPKAPK2 (0.41) MAPKAPK2HTR2BHTR5ASIRT2MAPT
SCHEMBL9612986 0.81 DYRK1A (0.44) GSK3B
SCHEMBL9613062 0.81 PIM1 (0.39) PIM1MAPTALDH1A1CYP1A2NPC1
SCHEMBL9613007 0.80 CA12 (0.40) PIM1MAPTALDH1A1NPC1SMN1; SMN2
SCHEMBL9612976 0.80 MAPKAPK2 (0.38) MAPKAPK2HTR2BHTR5APIM1ALDH1A1
SCHEMBL18160975 0.79 ENPP1 (0.42) MAPTALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012070535-A1 ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME JNC株式会社 (JP) 2012-05-31 WO disclosed