SCHEMBL9612975

SCHEMBL9612975

c1ccc2cc(-c3cc(-c4ccc(-c5c6ccccc6c(-c6cccc7ccccc67)c6ccccc56)cc4)ccn3)ccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.44
MAPKAPK2 P49137 1/20 0.43
HTR2B P41595 1/20 0.40
HTR5A P47898 1/20 0.40
SIRT2 Q8IXJ6 3/20 0.39
ALDH1A1 P00352 3/20 0.38
CYP1A2 P05177 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
CYP2C19 P33261 1/20 0.38
AR P10275 1/20 0.38
NFKB1 P19838 1/20 0.38
GFER P55789 1/20 0.38
NFKB2 Q00653 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9612971 0.90 MAPKAPK2 (0.40) PIM1MAPKAPK2HTR2BHTR5ASIRT2
SCHEMBL9613007 0.90 CA12 (0.40) PIM1ALDH1A1SMN1; SMN2NPC1KDM4E
SCHEMBL18160975 0.88 ENPP1 (0.42) ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL15977450 0.86 PIM1 (0.40) PIM1MAPKAPK2HTR2BHTR5ASIRT2
SCHEMBL9612973 0.86 MAPKAPK2 (0.41) MAPKAPK2HTR2BHTR5ASIRT2ALDH1A1
SCHEMBL25954713 0.86 PIM1 (0.50) PIM1MAPKAPK2HTR2BHTR5ASIRT2
SCHEMBL29360710 0.86 ESR1 (0.47) PIM1ALDH1A1MAPTESR1ESR2
SCHEMBL2775233 0.86 ESR1 (0.47) PIM1ALDH1A1MAPTESR1ESR2
SCHEMBL10017223 0.86 MAPK9 (0.43) PIM1MAPKAPK2HTR2BHTR5ASIRT2
SCHEMBL15977574 0.86 PIM1 (0.44) PIM1MAPKAPK2HTR2BHTR5ASIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012070535-A1 ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME JNC株式会社 (JP) 2012-05-31 WO disclosed