SCHEMBL9613110

SCHEMBL9613110

c1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5cccnc5-c5ccc6ccccc6c5)cc4)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK9 P45984 2/20 0.44
MAPK10 P53779 2/20 0.44
HTR2B P41595 1/20 0.42
HTR5A P47898 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
FEN1 P39748 1/20 0.40
ADORA2A P29274 3/20 0.39
ADORA1 P30542 3/20 0.39
CYP17A1 P05093 1/20 0.39
CYP19A1 P11511 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
CSNK1D P48730 4/20 0.36
MAPK11 Q15759 4/20 0.36
MAPK14 Q16539 4/20 0.36
DHODH Q02127 3/20 0.36
MAPK8 P45983 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9613112 0.91 COMT (0.43) MAPK9MAPK10HTR2BHTR5APTGS1
SCHEMBL9613107 0.89 MAPK9 (0.41) MAPK9MAPK10HTR2BHTR5APTGS1
SCHEMBL15977407 0.88 MAPK9 (0.45) MAPK9MAPK10HTR2BHTR5APTGS1
SCHEMBL9988734 0.86 MAPK9 (0.55) MAPK9MAPK10HTR2BHTR5APTGS1
SCHEMBL9613128 0.84 TNF (0.43) PTGS1PTGS2FEN1MAPK11MAPK14
SCHEMBL15977543 0.84 PTGS1 (0.44) MAPK9MAPK10HTR2BHTR5APTGS1
SCHEMBL15977555 0.84 PTGS1 (0.44) MAPK9MAPK10HTR2BHTR5APTGS1
SCHEMBL15977425 0.83 ADORA2A (0.46) MAPK9MAPK10HTR2BHTR5APTGS1
SCHEMBL10300900 0.82 PTGS2 (0.49) PTGS1PTGS2FEN1ESR1ESR2
SCHEMBL23814796 0.82 CYP17A1 (0.41) ADORA2AADORA1CYP17A1CYP19A1CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012070535-A1 ELECTRON TRANSPORT MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME JNC株式会社 (JP) 2012-05-31 WO disclosed