SCHEMBL9613345

SCHEMBL9613345

CN1C(=O)C(N=N)C(=O)N(C)C1=O

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.36
ALDH1A1 P00352 5/20 0.36
HSD17B10 Q99714 5/20 0.32
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
KDM4A O75164 1/20 0.32
KDM4C Q9H3R0 1/20 0.32
ADRA2C P18825 1/20 0.32
GSK3A P49840 1/20 0.32
GSK3B P49841 1/20 0.32
MGLL Q99685 1/20 0.32
GAA P10253 3/20 0.32
THRB P10828 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6698940 0.79 MAPT (0.39) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL200674 0.67 MAPT (0.41) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL8468520 0.65 MAPT (0.40) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL22628805 0.65 MAPT (0.40) MAPTALDH1A1HSD17B10MEN1KMT2A
Calcium SCHEMBL30891545 0.65 MAPT (0.40) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1263355 0.65 MAPT (0.40) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL4006398 0.65 MAPT (0.40) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL11820394 0.65 MAPT (0.40) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1263023 0.65 MAPT (0.40) MAPTALDH1A1HSD17B10MEN1KMT2A
SCHEMBL5915582 0.65 MAPT (0.61) MAPTALDH1A1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3296363-A1 AZO DYES Kemira Oyj (FI) 2018-03-21 EP disclosed
EP-3296362-A1 AZO DYES Kemira Oyj (FI) 2018-03-21 EP disclosed
US-8734532-B2 Azo dyes KEMIRA OYJ (FI) 2014-05-27 US disclosed
US-20130255006-A1 AZO DYES CHROMASCAPE, LLC 2013-10-03 US disclosed
WO-2012072634-A1 AZO DYES KEMIRA OYJ (FI) 2012-06-07 WO disclosed
EP-2457956-A1 Azo dyes Kemira Oyj (FI) 2012-05-30 EP disclosed