Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613345 | 0.79 | MAPT (0.36) | MAPTALDH1A1ADRA2CKMT2AHSD17B10 | |
| SCHEMBL200674 | 0.71 | MAPT (0.41) | MAPTALDH1A1ADRA2CKMT2AHSD17B10 | |
| Calcium SCHEMBL30891545 | 0.69 | MAPT (0.40) | MAPTALDH1A1ADRA2CKMT2AHSD17B10 | |
| SCHEMBL1263355 | 0.69 | MAPT (0.40) | MAPTALDH1A1ADRA2CKMT2AHSD17B10 | |
| SCHEMBL4006398 | 0.69 | MAPT (0.40) | MAPTALDH1A1ADRA2CKMT2AHSD17B10 | |
| SCHEMBL11820394 | 0.69 | MAPT (0.40) | MAPTALDH1A1ADRA2CKMT2AHSD17B10 | |
| SCHEMBL8468520 | 0.69 | MAPT (0.40) | MAPTALDH1A1ADRA2CKMT2AHSD17B10 | |
| SCHEMBL1263023 | 0.69 | MAPT (0.40) | MAPTALDH1A1ADRA2CKMT2AHSD17B10 | |
| SCHEMBL2601688 | 0.67 | — | — | |
| SCHEMBL17717929 | 0.67 | MAPT (0.47) | MAPTALDH1A1ADRA2CKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040049859-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | L'OREAL S.A. (FR) | 2004-03-18 | — | — | US | claimed |
| US-20040040098-A1 | Compositions for the oxidation dyeing of keratin fibers and dyeing processes using these compositions | L'OREAL | 2004-03-04 | — | — | US | claimed |
| US-20040025265-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | LANG GERARD (FR) | 2004-02-12 | — | — | US | claimed |
| US-20030159706-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | L'OREAL S.A. (FR) | 2003-08-28 | — | — | US | claimed |
| US-20040049859-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | L'OREAL S.A. (FR) | 2004-03-18 | — | — | US | disclosed |
| US-20040040098-A1 | Compositions for the oxidation dyeing of keratin fibers and dyeing processes using these compositions | L'OREAL | 2004-03-04 | — | — | US | disclosed |
| US-20040025265-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | LANG GERARD (FR) | 2004-02-12 | — | — | US | disclosed |
| US-20040016062-A1 | Nondyeing composition containing a precursor and an oxidation reaction catalyst | L'OREAL (FR) | 2004-01-29 | — | — | US | disclosed |
| US-20030159706-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | L'OREAL S.A. (FR) | 2003-08-28 | — | — | US | disclosed |
| EP-0843723-A1 | METHOD FOR ENHANCING THE ACTIVITY OF AN ENZYME, COMPOUNDS SHOWING ENZYME ACTIVITY ENHANCEMENT, AND DETERGENTS CONTAINING SUCH COMPOUNDS | Ciba SC Holding AG (CH) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997006244-A1 | METHOD FOR ENHANCING THE ACTIVITY OF AN ENZYME, COMPOUNDS SHOWING ENZYME ACTIVITY ENHANCEMENT, AND DETERGENTS CONTAINING SUCH COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1997-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030159706-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | KRT18, LPO, MPO | MAPT 1208/4885ALDH1A1 347/4885ADRA2C 4581/4885 |
| US-20040025265-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | KRT18, LPO, ALDH1A2 | MAPT 1295/4885ALDH1A1 494/4885ADRA2C 4694/4885 |
| US-20040049859-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | KRT18, COXFA4, LPO | MAPT 1092/4885ALDH1A1 322/4885ADRA2C 4571/4885 |
| US-20040040098-A1 | Compositions for the oxidation dyeing of keratin fibers and dyeing processes using these compositions | KRT18, PPOX, POR | MAPT 2195/4885ALDH1A1 164/4885ADRA2C 2938/4885 |
| US-20040016062-A1 | Nondyeing composition containing a precursor and an oxidation reaction catalyst | KRT18, CUTA, PPOX | MAPT 1127/4885ALDH1A1 1106/4885ADRA2C 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.