Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069547 | 0.86 | F10 (0.76) | F10GAAUSP2KMT2AMEN1 | |
| SCHEMBL7072134 | 0.86 | F10 (0.63) | F10GAAUSP2KMT2AMEN1 | |
| SCHEMBL7071910 | 0.86 | F10 (0.63) | F10TSHRRECQLGAAUSP2 | |
| SCHEMBL7074220 | 0.85 | LMNA (0.71) | F10GAAUSP2KMT2AMEN1 | |
| Acetic Acid SCHEMBL27525136 | 0.83 | LMNA (0.62) | F10GAAUSP2SMN1; SMN2KMT2A | |
| Acetic Acid SCHEMBL27550434 | 0.82 | F10 (0.70) | F10GAAUSP2KMT2AMEN1 | |
| Acetic Acid SCHEMBL27530032 | 0.82 | F10 (0.59) | F10GAAUSP2KMT2AMEN1 | |
| Acetic Acid SCHEMBL28744327 | 0.82 | LMNA (0.70) | F10GAAUSP2SMN1; SMN2KMT2A | |
| SCHEMBL5735860 | 0.81 | F10 (0.80) | F10GAASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7074438 | 0.81 | F10 (0.69) | F10KMT2AMEN1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012071469-A2 | HISTONE DEMETHYLASE INHIBITORS AND USES THEREOF FOR TREATMENT O F CANCER | NEVADA CANCER INSTITUTE (US) | 2012-05-31 | — | — | WO | disclosed |