Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 7/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9613924 | 0.92 | KMT2A (0.51) | SLC6A2SLC6A4TDP1HTR1BKCNA3 | |
| Formic Acid SCHEMBL9520736 | 0.81 | TDP1 (0.46) | SLC6A2SLC6A4TDP1KMT2AMTNR1A | |
| Formic Acid SCHEMBL9520738 | 0.81 | TDP1 (0.46) | SLC6A2SLC6A4TDP1KMT2AMTNR1A | |
| Oxalic Acid SCHEMBL9613773 | 0.81 | KMT2A (0.50) | SLC6A2SLC6A4TDP1HTR1BKCNA3 | |
| Dapoxetine SCHEMBL3679561 | 0.81 | HTR1B (0.57) | SLC6A4HTR1BKCNA3KMT2AHTR1D | |
| Dapoxetine SCHEMBL34479 | 0.81 | HTR1B (0.57) | SLC6A4HTR1BKCNA3KMT2AHTR1D | |
| Dapoxetine SCHEMBL29387056 | 0.81 | HTR1B (0.57) | SLC6A4HTR1BKCNA3KMT2AHTR1D | |
| Dapoxetine SCHEMBL3672581 | 0.81 | HTR1B (0.57) | SLC6A4HTR1BKCNA3KMT2AHTR1D | |
| Dapoxetine SCHEMBL30600097 | 0.81 | HTR1B (0.57) | SLC6A4HTR1BKCNA3KMT2AHTR1D | |
| Dapoxetine SCHEMBL29488428 | 0.81 | HTR1B (0.57) | SLC6A4HTR1BKCNA3KMT2AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135947-A | Treatment of depression, eating disorders, and alcoholism | ELI LILLY AND COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0288188-B1 | 1-PHENYL-3-NAPHTHALENYLOXY-PROPANAMINES | ELI LILLY AND COMPANY (US) | 1991-10-16 | — | — | EP | disclosed |
| EP-0288188-A1 | 1-Phenyl-3-naphthalenyloxy-propanamines | ELI LILLY AND COMPANY (US) | 1988-10-26 | — | — | EP | disclosed |