Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.41 |
| ▸ | LPAR6 | P43657 | 5/20 | 0.41 |
| ▸ | LPAR4 | Q99677 | 5/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17213542 | 0.96 | TSHR (0.46) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL12024300 | 0.94 | TSHR (0.48) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL13563001 | 0.89 | TSHR (0.48) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL27424769 | 0.88 | USP2 (0.46) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL14642724 | 0.87 | LPAR1 (0.39) | LPAR1LPAR3LPAR2LPAR6LPAR4 | |
| SCHEMBL12418703 | 0.87 | LPAR1 (0.42) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL209403 | 0.87 | HSD17B10 (0.50) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL18544663 | 0.85 | LPAR1 (0.42) | HSD17B10TDP1LPAR1LPAR3LPAR2 | |
| SCHEMBL17213404 | 0.85 | USP2 (0.47) | HSD17B10LPAR1LPAR3LPAR2LPAR6 | |
| SCHEMBL14642721 | 0.85 | ALDH1A1 (0.48) | LPAR1LPAR3LPAR2LPAR6LPAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164124-A | Preparation of ethylene and propylene oxide adducts, nonionic surfactants | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1992-11-17 | — | — | US | disclosed |