Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TK1 | P04183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25077369 | 0.84 | TK1 (0.48) | ALDH1A1TK1 | |
| SCHEMBL25077450 | 0.84 | TK1 (0.48) | ALDH1A1TK1 | |
| SCHEMBL25284468 | 0.84 | TK1 (0.48) | ALDH1A1TK1 | |
| SCHEMBL25077124 | 0.84 | TK1 (0.48) | ALDH1A1TK1 | |
| SCHEMBL25293956 | 0.84 | TK1 (0.48) | ALDH1A1TK1 | |
| SCHEMBL25077460 | 0.84 | TK1 (0.48) | ALDH1A1TK1 | |
| SCHEMBL25245658 | 0.84 | TK1 (0.48) | ALDH1A1TK1 | |
| SCHEMBL25077082 | 0.84 | TK1 (0.48) | ALDH1A1TK1 | |
| SCHEMBL25077451 | 0.84 | TK1 (0.48) | ALDH1A1TK1 | |
| SCHEMBL25286339 | 0.84 | TK1 (0.48) | ALDH1A1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116992-A | Antitumor | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1992-05-26 | — | — | US | disclosed |