Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | PTGES | O14684 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613997 | 0.92 | PPARA (0.50) | MAPTRXFP1TRPA1CYSLTR2CYSLTR1 | |
| SCHEMBL9614100 | 0.92 | PPARA (0.50) | MAPTRXFP1TRPA1CYSLTR2CYSLTR1 | |
| SCHEMBL1863852 | 0.86 | PPARG (0.45) | CYSLTR2CYSLTR1PPARGSMN1; SMN2 | |
| SCHEMBL10420689 | 0.83 | PPARG (0.53) | MAPTRXFP1TRPA1S1PR2S1PR4 | |
| SCHEMBL9696793 | 0.82 | PPARA (0.43) | CYSLTR2CYSLTR1ALOX5PTGESPPARG | |
| SCHEMBL1858556 | 0.82 | GRIK1 (0.49) | MAPTRXFP1ALOX5PTGESPPARG | |
| SCHEMBL5511989 | 0.79 | MAPT (0.60) | MAPTRXFP1TRPA1S1PR2S1PR4 | |
| SCHEMBL7102236 | 0.79 | MAPT (0.60) | MAPTRXFP1TRPA1S1PR2S1PR4 | |
| SCHEMBL11291692 | 0.79 | MAPT (0.60) | MAPTRXFP1TRPA1S1PR2S1PR4 | |
| SCHEMBL11294877 | 0.79 | MAPT (0.60) | MAPTRXFP1TRPA1S1PR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |