Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614100 | 1.00 | PPARA (0.50) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL9613875 | 0.92 | MAPT (0.50) | PPARGTRPA1CYSLTR2CYSLTR1MAPT | |
| SCHEMBL9696793 | 0.91 | PPARA (0.43) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10419191 | 0.84 | PPARG (0.47) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10420481 | 0.82 | PPARA (0.49) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10418815 | 0.81 | CYP2C9 (0.49) | PPARAPPARGMAPT | |
| SCHEMBL1863852 | 0.79 | PPARG (0.45) | PPARAPPARGCYSLTR2CYSLTR1CNR2 | |
| SCHEMBL9614128 | 0.79 | PPARG (0.43) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL9814962 | 0.78 | PPARG (0.43) | PPARAPPARGTDP1MAPT | |
| SCHEMBL11208077 | 0.78 | PPARA (0.56) | PPARAPPARGPLAAT3PLAAT5PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |