Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.66 |
| ▸ | PPARG | P37231 | 16/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614120 | 1.00 | PPARA (0.66) | PPARAPPARGNPC1DRD2DRD4 | |
| SCHEMBL9614051 | 0.99 | PPARA (0.67) | PPARAPPARGNPC1DRD2DRD4 | |
| SCHEMBL9614187 | 0.93 | PPARG (0.55) | PPARAPPARGCTRC | |
| SCHEMBL9858489 | 0.92 | PPARG (0.76) | PPARAPPARG | |
| SCHEMBL9614177 | 0.90 | PPARG (0.61) | PPARAPPARGDRD2DRD4DRD3 | |
| SCHEMBL9858456 | 0.88 | PPARG (0.50) | PPARAPPARGNPC1CTRC | |
| SCHEMBL9613979 | 0.88 | PPARG (0.63) | PPARAPPARGDRD2DRD4DRD3 | |
| SCHEMBL9857906 | 0.87 | PPARG (0.49) | PPARAPPARGDRD2DRD4DRD3 | |
| SCHEMBL9696342 | 0.87 | PPARG (0.51) | PPARAPPARGCTRC | |
| SCHEMBL10419185 | 0.86 | PPARA (0.78) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |