Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.49 |
| ▸ | PPARA | Q07869 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696970 | 0.99 | PPARG (0.50) | PPARGPPARAKDM4ESMN1; SMN2DRD2 | |
| SCHEMBL9614187 | 0.93 | PPARG (0.55) | PPARGPPARACTRCPTGESALOX5 | |
| SCHEMBL9614177 | 0.90 | PPARG (0.61) | PPARGPPARADRD2DRD4DRD3 | |
| SCHEMBL9858456 | 0.88 | PPARG (0.50) | PPARGPPARACTRCPTGESALOX5 | |
| SCHEMBL9613979 | 0.88 | PPARG (0.63) | PPARGPPARADRD2DRD4DRD3 | |
| SCHEMBL9614120 | 0.87 | PPARA (0.66) | PPARGPPARADRD2DRD4DRD3 | |
| SCHEMBL9614013 | 0.87 | PPARA (0.66) | PPARGPPARADRD2DRD4DRD3 | |
| SCHEMBL9696342 | 0.87 | PPARG (0.51) | PPARGPPARACTRCPTGESALOX5 | |
| SCHEMBL9614051 | 0.86 | PPARA (0.67) | PPARGPPARADRD2DRD4DRD3 | |
| SCHEMBL9614241 | 0.84 | PPARG (0.50) | PPARGPPARASMN1; SMN2CTRCPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279162-B1 | CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0279162-A1 | Carbonic acid derivatives, process for their preparation and pharmaceuticals containing them | Roche Diagnostics GmbH (DE) | 1988-08-24 | — | — | EP | disclosed |