Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.55 |
| ▸ | PPARG | P37231 | 8/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9613870 | 0.81 | PPARA (0.51) | PPARAPPARG | |
| SCHEMBL9614063 | 0.79 | PPARA (0.47) | PPARAPPARGPTGESALOX5S1PR2 | |
| SCHEMBL11317725 | 0.79 | PPARA (0.76) | PPARAPPARGPTGESALOX5ALDH1A1 | |
| SCHEMBL9613878 | 0.78 | PPARA (0.47) | PPARAPPARGMEN1KMT2AS1PR2 | |
| SCHEMBL11847654 | 0.75 | ALDH1A1 (0.54) | PPARAPPARGPTGESALOX5RARB | |
| SCHEMBL9614214 | 0.75 | PPARA (0.62) | PPARAPPARGPTGESALOX5 | |
| SCHEMBL9613990 | 0.75 | PPARA (0.62) | PPARAPPARGPTGESALOX5 | |
| SCHEMBL9613951 | 0.75 | PPARA (0.67) | PPARAPPARG | |
| SCHEMBL8775067 | 0.74 | RARB (0.65) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL14672531 | 0.74 | RARB (0.65) | RARBALDH1A1MEN1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |