Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.71 |
| ▸ | PPARA | Q07869 | 16/20 | 0.71 |
| ▸ | ALOX5 | P09917 | 13/20 | 0.71 |
| ▸ | PTGES | O14684 | 11/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614180 | 0.95 | PPARG (0.65) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9614074 | 0.94 | PPARG (0.64) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9613848 | 0.85 | PPARG (0.81) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9858491 | 0.82 | PPARG (0.75) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9857889 | 0.81 | PPARG (0.74) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9858468 | 0.81 | PPARG (0.74) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9613827 | 0.81 | PPARG (0.73) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9614194 | 0.81 | PPARG (0.53) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9614203 | 0.80 | PPARG (0.72) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9613814 | 0.80 | PPARG (0.72) | PPARGPPARAALOX5PTGESALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |