Phthalic Acid

Phthalic Acid

SCHEMBL9614378

O=C(O)c1ccccc1C(=O)O.O=C1C=CC(=O)O1.OCCO

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
ALOX15 P16050 1/20 0.54
KMT2A Q03164 2/20 0.44
APEX1 P27695 1/20 0.44
AKR1C3 P42330 1/20 0.44
KDM4E B2RXH2 2/20 0.43
CYP2C9 P11712 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
HMGB1 P09429 1/20 0.42
HPGD P15428 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA7 P43166 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CA9 Q16790 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
CA14 Q9ULX7 1/20 0.42
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL3811685 0.92 ALDH1A1 (0.64) ALDH1A1ALOX15AKR1C3KDM4ECYP2C9
Phthalic Acid SCHEMBL5888909 0.83 ALDH1A1 (0.78) ALDH1A1ALOX15KMT2AAPEX1AKR1C3
Phthalic Acid SCHEMBL1532704 0.83 ALDH1A1 (0.78) ALDH1A1ALOX15KMT2AAPEX1AKR1C3
Phthalic Acid SCHEMBL30182240 0.83 ALDH1A1 (0.78) ALDH1A1ALOX15KMT2AAPEX1AKR1C3
Phthalic Acid SCHEMBL3671128 0.83 ALDH1A1 (0.78) ALDH1A1ALOX15KMT2AAPEX1AKR1C3
Phthalic Acid SCHEMBL27783718 0.81 ALDH1A1 (0.74) ALDH1A1ALOX15KMT2AAPEX1AKR1C3
Maleic Anhydride SCHEMBL10920639 0.81
Phthalic Acid SCHEMBL27901342 0.81 ALDH1A1 (0.74) ALDH1A1ALOX15KMT2AAPEX1AKR1C3
Salicylic Acid SCHEMBL28422251 0.81 ALDH1A1 (0.69) ALDH1A1ALOX15KMT2AKDM4ECYP2C9
Toluic Acid SCHEMBL11322573 0.79 MYC (0.49) ALDH1A1ALOX15KMT2AAKR1C3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0262464-B1 POLYAMINE-POLYENE ULTRAVIOLET COATINGS DSM N.V. (NL) 1992-06-24 EP disclosed
EP-0462200-A4 PHOTOCURABLE POLYAMINE-ENE COMPOSITIONS HAVING IMPROVED CURE SPEED 1992-01-29 EP disclosed
EP-0462200-A1 PHOTOCURABLE POLYAMINE-ENE COMPOSITIONS HAVING IMPROVED CURE SPEED DSM N.V. (NL) 1991-12-27 EP disclosed
WO-1990010659-A1 PHOTOCURABLE POLYAMINE-ENE COMPOSITIONS HAVING IMPROVED CURE SPEED DESOTO, INC. (US) 1990-09-20 WO disclosed
US-4943600-A BLEND OF AMINOACRYLATE COPOLYMER, UNSATURATED POLYESTER AND ALLYL TERMINATED POLYESTER DESOTO, INC. (US) 1990-07-24 US disclosed
US-4761435-A POLYETHYLENICALLY UNSATURATED MATERIAL, POLYAMINE RESIN, ARYL KETONE PHOTOSENSITIZER DESOTO, INC. (US) 1988-08-02 US disclosed
EP-0262464-A2 Polyamine-polyene ultraviolet coatings DSM N.V. (NL) 1988-04-06 EP disclosed
US-3945875-A UNSATURATED ISOCYANATES, ADHESIVES, PEROXIDE CURING AGENT THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-03-23 US disclosed