Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614320 | 0.97 | TRPV4 (0.49) | TRPV4TSHRMAPTCA12CA1 | |
| SCHEMBL10076070 | 0.84 | HSD17B10 (0.42) | TRPV4TSHRMAPTCA12CA1 | |
| SCHEMBL590866 | 0.81 | MAPT (0.50) | TRPV4TSHRMAPTCA12CA1 | |
| SCHEMBL11038732 | 0.78 | TRPV4 (0.36) | TRPV4TDP1ALDH1A1HSD17B10 | |
| SCHEMBL9614394 | 0.78 | CA12 (0.43) | TSHRMAPTCA12CA1CA2 | |
| SCHEMBL19274350 | 0.77 | HSD17B10 (0.40) | TRPV4TSHRMAPTCA12CA1 | |
| SCHEMBL4925230 | 0.74 | TRPV4 (0.33) | TRPV4 | |
| SCHEMBL9614315 | 0.73 | HTT (0.39) | TRPV4TSHRMAPTTDP1ALDH1A1 | |
| SCHEMBL17695444 | 0.73 | HSD17B10 (0.39) | TSHRMAPTTDP1ALDH1A1MEN1 | |
| SCHEMBL19939980 | 0.72 | HTT (0.35) | TRPV4TSHRMAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396732-A4 | FLUORESCENT IMMUNOASSAYS AND FLUORESCENT COMPOUNDS AND TRACERS THEREFORE | — | 1992-10-07 | — | — | EP | disclosed |
| EP-0396732-A1 | FLUORESCENT IMMUNOASSAYS AND FLUORESCENT COMPOUNDS AND TRACERS THEREFORE | DOWBEN, Robert M. (US) | 1990-11-14 | — | — | EP | disclosed |
| WO-1990005916-A1 | FLUORESCENT IMMUNOASSAYS AND FLUORESCENT COMPOUNDS AND TRACERS THEREFORE | DOWBEN ROBERT M (US) | 1990-05-31 | — | — | WO | disclosed |