Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.60 |
| ▸ | CDC25B | P30305 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11225742 | 0.95 | LIG1 (0.73) | LIG1MAPTLMNAESR1ESR2 | |
| SCHEMBL63564 | 0.91 | AKR1C3 (0.76) | LIG1MAPTLMNAESR1ESR2 | |
| SCHEMBL29360039 | 0.91 | AKR1C3 (0.76) | LIG1MAPTLMNAESR1ESR2 | |
| SCHEMBL7849772 | 0.89 | LIG1 (0.66) | LIG1MAPTLMNAESR1ESR2 | |
| SCHEMBL10418498 | 0.89 | LIG1 (0.66) | LIG1MAPTLMNAESR1ESR2 | |
| SCHEMBL27537001 | 0.89 | LIG1 (0.66) | LIG1MAPTLMNAESR1ESR2 | |
| SCHEMBL29512266 | 0.89 | LIG1 (1.00) | LIG1MAPTLMNAESR1ESR2 | |
| SCHEMBL9851200 | 0.89 | LIG1 (0.70) | LIG1MAPTLMNAESR1ESR2 | |
| SCHEMBL1568564 | 0.89 | LIG1 (1.00) | LIG1MAPTLMNAESR1ESR2 | |
| SCHEMBL398083 | 0.85 | LIG1 (0.66) | LIG1MAPTLMNAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479878-A1 | PROCESS FOR PREPARING 1,4-BIS-(4-HYDROXYBENZOYL)-BENZENE. | HOECHST AG (DE) | 1992-04-15 | — | — | EP | claimed |
| WO-1991000256-A1 | PROCESS FOR PREPARING 1,4-BIS-(4-HYDROXYBENZOYL)-BENZENE | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-10 | — | — | WO | claimed |
| CN-110312752-A | Poly (ether ketone) polymers, corresponding methods of synthesis and polymer compositions, and articles made therefrom | 索尔维特殊聚合物美国有限责任公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-110267935-A | Method for reducing metal concentration in monomer composition comprising bis (benzoyl) benzene | 索尔维特殊聚合物美国有限责任公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-110248984-A | Poly- (ether ketone ketone) polymer, corresponding synthetic method and polymer composition and the product being made from it | 索尔维特殊聚合物美国有限责任公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-1974631-A | Prepn process of poly (ether-ketone-ketone) as high performance polymer | UNIV JILIN (CN) | 2007-06-06 | — | — | CN | disclosed |
| EP-0386542-A2 | Process for preparation of aromatic polyetherketons | BAYER AG (DE) | 1990-09-12 | — | — | EP | disclosed |