Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.50 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.50 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29963659 | 1.00 | LIG1 (0.66) | LIG1LMNAMAPTHPGDESR1 | |
| SCHEMBL10613768 | 0.94 | LMNA (0.61) | LIG1LMNAMAPTHPGDESR1 | |
| SCHEMBL10759830 | 0.92 | CES2 (0.62) | LIG1LMNAMAPTHPGDCES2 | |
| SCHEMBL10613762 | 0.90 | LIG1 (0.54) | LIG1ESR1ESR2CES2CES1 | |
| SCHEMBL29377967 | 0.86 | CES2 (0.56) | LIG1LMNAMAPTHPGDHTT | |
| SCHEMBL896769 | 0.86 | CES2 (0.56) | LIG1LMNAMAPTHPGDHTT | |
| SCHEMBL9507199 | 0.86 | CDC25B (0.60) | LIG1LMNAMAPTHPGDCES2 | |
| SCHEMBL333008 | 0.85 | AKR1C3 (0.61) | LMNAMAPTHPGDCES2CES1 | |
| SCHEMBL29433447 | 0.85 | AKR1C3 (0.61) | LMNAMAPTHPGDCES2CES1 | |
| SCHEMBL9614636 | 0.85 | LIG1 (0.79) | LIG1LMNAMAPTHPGDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110761074-B | Environment-friendly low-temperature water-repellent and oil-repellent composition | 乳源东阳光氟有限公司 | 2023-08-08 | — | — | CN | claimed |
| EP-0167240-B1 | PURIFICATION OF 4-FLUORO-4'-HYDROXY-BENZOPHENONE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-17 | — | — | EP | claimed |
| US-4612399-A | Purification of 4-fluoro-4'-hydroxybenzophenone | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-16 | — | — | US | claimed |
| EP-0167240-A1 | Purification of 4-fluoro-4'-hydroxy-benzophenone | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-01-08 | — | — | EP | claimed |
| CN-110761074-B | Environment-friendly low-temperature water-repellent and oil-repellent composition | 乳源东阳光氟有限公司 | 2023-08-08 | — | — | CN | disclosed |
| US-9061981-B2 | Diphenyl substituted cyclohexane derivatives, useful as modulators of the estrogen receptors beta | ACADIA PHARMACEUTICALS INC. (US) | 2015-06-23 | — | — | US | disclosed |
| US-20140275284-A1 | DIPHENYL SUBSTITUTED CYCLOHEXANE DERIVATIVES, USEFUL AS MODULATORS OF THE ESTROGEN RECEPTORS BETA | ACADIA PHARMACEUTICALS INC. (US) | 2014-09-18 | — | — | US | disclosed |
| WO-2014125121-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING NEURODEGENERATIVE DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2014-08-21 | — | — | WO | disclosed |
| EP-2739600-A1 | DIPHENYL SUBSTITUTED CYCLOHEXANE DERIVATIVES, USEFUL AS MODULATORS OF THE ESTROGEN RECEPTORS BETA | Acadia Pharmaceuticals Inc. (US) | 2014-06-11 | — | — | EP | disclosed |
| EP-2200994-B1 | CONDENSED COMPOUNDS WITH ACTIVITY AT ESTROGEN RECEPTORS | ACADIA PHARM INC (US) | 2014-01-22 | — | — | EP | disclosed |
| US-8470872-B2 | Compounds with activity at estrogen receptors | ACADIA PHARMACEUTICALS INC. (US) | 2013-06-25 | — | — | US | disclosed |
| WO-2013017619-A1 | DIPHENYL SUBSTITUTED CYCLOHEXANE DERIVATIVES, USEFUL AS MODULATORS OF THE ESTROGEN RECEPTORS BETA | ACADIA PHARMACEUTICALS INC. (US) | 2013-02-07 | — | — | WO | disclosed |
| US-4612399-A | Purification of 4-fluoro-4'-hydroxybenzophenone | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-16 | — | — | US | disclosed |
| US-4612399-A | Purification of 4-fluoro-4'-hydroxybenzophenone | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-16 | — | — | US | disclosed |
| US-4604485-A | Chemical process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-08-05 | — | — | US | disclosed |
| US-4599452-A | Chemical process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-07-08 | — | — | US | disclosed |
| EP-0167240-A1 | Purification of 4-fluoro-4'-hydroxy-benzophenone | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-01-08 | — | — | EP | disclosed |
| EP-0167240-A1 | Purification of 4-fluoro-4'-hydroxy-benzophenone | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-01-08 | — | — | EP | disclosed |
| EP-0128693-A2 | Process for the preparation of 4-hydroxybenzophenones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-12-19 | — | — | EP | disclosed |
| EP-0128692-A2 | Process for the preparation of 4-hydroxy-benzophenones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275284-A1 | DIPHENYL SUBSTITUTED CYCLOHEXANE DERIVATIVES, USEFUL AS MODULATORS OF THE ESTROGEN RECEPTORS BETA | ESR2, GPER1, ESRRA | LIG1 4515/4885LMNA 3260/4885MAPT 4100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.