Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Fluoride Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.71 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL28444278 | 0.96 | DNM1 (0.75) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Fluoride Ion SCHEMBL19875 | 0.96 | DNM1 (0.75) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Fluoride Ion SCHEMBL28465809 | 0.96 | DNM1 (0.75) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Fluoride Ion SCHEMBL28959250 | 0.96 | DNM1 (0.75) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Fluoride Ion SCHEMBL431311 | 0.93 | DNM1 (0.71) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Fluoride SCHEMBL9615257 | 0.93 | DNM1 (0.71) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Fluoride Ion SCHEMBL64799 | 0.93 | DNM1 (0.71) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Fluoride Ion SCHEMBL22472141 | 0.93 | DNM1 (0.71) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| SCHEMBL29496398 | 0.93 | DNM1 (0.80) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL23198627 | 0.89 | DNM1 (0.75) | DNM1BDKRB2TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4124195-A | — | — | None | — | — | JP | disclosed |
| JP-H04124195-A | NEW METALLIC FLUORIDE COMPLEX OF QUATERNARY PHOSPHONIUM FLUORIDE, ITS PRODUCTION, FLUORINATING AGENT AND DESILYLATING AGENT | HOKKO CHEM IND CO LTD | 1992-04-24 | — | — | JP | disclosed |