Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10627221 | 0.97 | CA2 (0.41) | CA2TSHRTDP1CA1CA9 | |
| Bicarbonate SCHEMBL7609157 | 0.97 | CA2 (0.41) | CA2TSHRTDP1CA1CA9 | |
| Bicarbonate SCHEMBL8024219 | 0.93 | CA2 (0.44) | CA2TSHRTDP1CA1CA9 | |
| Hydrogen Peroxide SCHEMBL2572902 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL6413575 | 0.89 | CA2 (0.47) | CA2TSHRTDP1CA1CA9 | |
| Hydrogen Peroxide SCHEMBL6658306 | 0.89 | — | — | |
| Bicarbonate SCHEMBL27815734 | 0.87 | CA2 (0.39) | CA2TSHRTDP1CA1CA9 | |
| Ammonia Solution, Strong SCHEMBL21383092 | 0.86 | — | — | |
| Ammonia Solution, Strong SCHEMBL506346 | 0.86 | — | — | |
| Hydrogen Peroxide SCHEMBL2202104 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122611-A | Oxidative condensation of active methylene or methine containing compound with a p-phenylene diamine component in methylene chloride solvent | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |