SCHEMBL9615388

SCHEMBL9615388

CC(C)(C)c1cc(C(=O)O)c(O)c(C(C)(C)c2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A2 O00482 1/20 0.45
NR5A1 Q13285 1/20 0.45
AKR1C2 P52895 1/20 0.44
AKR1C1 Q04828 1/20 0.44
CYP3A4 P08684 2/20 0.41
CYP2C9 P11712 2/20 0.41
TSHR P16473 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
RXRB P28702 4/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 2/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
ALOX5 P09917 2/20 0.40
PTGS2 P35354 2/20 0.40
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
THRB P10828 1/20 0.40
ALOX12 P18054 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1129729 0.92 ESR1 (0.46) NR5A2NR5A1AKR1C2AKR1C1CYP3A4
Water SCHEMBL9852464 0.91 ESR1 (0.44) NR5A2NR5A1AKR1C2AKR1C1CYP3A4
SCHEMBL7084776 0.91 ESR1 (0.44) NR5A2NR5A1AKR1C2AKR1C1CYP3A4
Water SCHEMBL9852463 0.89 ESR1 (0.43) NR5A2NR5A1AKR1C2AKR1C1CYP3A4
SCHEMBL10520182 0.89 NR5A2 (0.50) NR5A2NR5A1AKR1C2AKR1C1CYP3A4
SCHEMBL9615386 0.88 NR5A2 (0.48) NR5A2NR5A1AKR1C2AKR1C1CYP3A4
SCHEMBL9251401 0.85 CYP2C9 (0.39) NR5A2NR5A1AKR1C2AKR1C1CYP3A4
SCHEMBL3019692 0.84 CSNK2A1 (0.42) AKR1C2AKR1C1CYP3A4CYP2C9TSHR
SCHEMBL5143831 0.84 SHBG (0.38) NR5A2NR5A1AKR1C2AKR1C1CYP3A4
SCHEMBL132940 0.83 NR5A2 (0.55) NR5A2NR5A1AKR1C2AKR1C1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5141557-A Mixture of benzoic acid salt, anionic surfactant, and novolak phenolic resin BROTHER KOGYO KABUSHIKI KAISHA (JP) 1992-08-25 US disclosed
US-5128309-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1992-07-07 US disclosed