SCHEMBL9615409

SCHEMBL9615409

CC(O)c1cc2c(o1)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 4/20 0.73
MEN1 O00255 6/20 0.48
KMT2A Q03164 6/20 0.48
MAPT P10636 6/20 0.48
MAOA P21397 5/20 0.48
HPGD P15428 4/20 0.41
MCL1 Q07820 4/20 0.41
TDP1 Q9NUW8 3/20 0.41
POLB P06746 3/20 0.41
BLM P54132 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
PABPC1 P11940 1/20 0.41
CSNK1A1 P48729 1/20 0.41
CSNK1D P48730 1/20 0.41
PLEC Q15149 1/20 0.41
CSNK1G1 Q9HCP0 1/20 0.41
ALDH1A1 P00352 5/20 0.41
KDM4E B2RXH2 4/20 0.41
MAPK1 P28482 4/20 0.41
RECQL P46063 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2801404 0.84 STAT3 (1.00) STAT3MEN1KMT2AMAPTMAOA
SCHEMBL10037431 0.84 STAT3 (1.00) STAT3MEN1KMT2AMAPTMAOA
SCHEMBL866692 0.84 STAT3 (1.00) STAT3MEN1KMT2AMAPTMAOA
SCHEMBL10037441 0.80 STAT3 (0.81) STAT3MEN1KMT2AMAPTMAOA
SCHEMBL22325644 0.78 STAT3 (0.79) STAT3MEN1KMT2AMAPTMAOA
SCHEMBL29365382 0.77 STAT3 (0.69) STAT3MEN1KMT2AMAPTMAOA
SCHEMBL1887185 0.77 STAT3 (0.69) STAT3MEN1KMT2AMAPTMAOA
SCHEMBL13843896 0.75 STAT3 (0.84) STAT3MEN1KMT2AMAPTMAOA
SCHEMBL22325626 0.73 STAT3 (0.80) STAT3MEN1KMT2AMAPTMAOA
SCHEMBL22325634 0.73 STAT3 (0.80) STAT3MEN1KMT2AMAPTMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4139177-A None JP disclosed
JP-H04139177-A FURALBENZOQUINONE DERIVATIVE, ITS PRODUCTION AND CARCINOSTATIC AGENT DAINIPPON INK & CHEM INC 1992-05-13 JP disclosed