Oxazole

Oxazole

SCHEMBL9615519

c1ccc2c(c1)ccc1ocnc12.c1cocn1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.37
CYP3A4 P08684 2/20 0.37
LMNA P02545 1/20 0.37
APEX1 P27695 1/20 0.37
MAPK1 P28482 1/20 0.37
PMP22 Q01453 1/20 0.37
TDP1 Q9NUW8 4/20 0.37
ALDH1A1 P00352 5/20 0.35
HSD17B10 Q99714 4/20 0.35
CYP2A6 P11509 2/20 0.35
TSHR P16473 2/20 0.35
PLAU P00749 2/20 0.34
F12 P00748 1/20 0.34
NCF1 P14598 1/20 0.34
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
BACE1 P56817 1/20 0.34
HPRT1 P00492 1/20 0.33
PLG P00747 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50811 0.86 TDP1 (0.48) MAPTCYP3A4LMNAAPEX1MAPK1
Benzo[D]Oxazole SCHEMBL28790463 0.84 PRKD1 (0.31)
Iodide SCHEMBL16916967 0.84 TDP1 (0.46) MAPTCYP3A4LMNAAPEX1MAPK1
Phosphine SCHEMBL28474623 0.84 TDP1 (0.46) MAPTCYP3A4LMNAAPEX1MAPK1
Phenanthrene SCHEMBL27708213 0.84 ALDH1A1 (0.50) MAPTCYP3A4LMNAAPEX1MAPK1
Pyridine SCHEMBL10336881 0.83 TDP1 (0.40) MAPTCYP3A4LMNAAPEX1MAPK1
Formaldehyde SCHEMBL27472811 0.81 ALDH1A1 (0.43) MAPTCYP3A4LMNAAPEX1MAPK1
SCHEMBL28466736 0.81 ALDH1A1 (0.43) MAPTCYP3A4LMNATDP1ALDH1A1
Anthracene SCHEMBL28071192 0.81 ALDH1A1 (0.43) MAPTCYP3A4LMNAAPEX1MAPK1
Quinoxaline SCHEMBL27740738 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5128238-A Developing both a negative silver halide color photographic material and an internal latent image type positive silver halide color photographic material with the same developer FUJI PHOTO FILM CO., LTD. (JP) 1992-07-07 US claimed
EP-0343604-A2 Method of forming color images Fuji Photo Film Co., Ltd. (JP) 1989-11-29 EP claimed
US-5128238-A Developing both a negative silver halide color photographic material and an internal latent image type positive silver halide color photographic material with the same developer FUJI PHOTO FILM CO., LTD. (JP) 1992-07-07 US disclosed
EP-0343604-A2 Method of forming color images Fuji Photo Film Co., Ltd. (JP) 1989-11-29 EP disclosed