SCHEMBL9615544

SCHEMBL9615544

Cc1nc2cc(C#N)c(Cl)cc2[nH]1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.49
EGLN1 Q9GZT9 1/20 0.47
PGK1 P00558 1/20 0.46
RHEB Q15382 1/20 0.43
MAPT P10636 3/20 0.41
KDM4E B2RXH2 2/20 0.41
POLB P06746 2/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 2/20 0.41
GAA P10253 2/20 0.40
CSNK1D P48730 1/20 0.39
CSNK1G2 P78368 1/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNA4 P43681 1/20 0.39
PSMB8 P28062 1/20 0.38
PKM P14618 1/20 0.38
PARP1 P09874 1/20 0.37
HSP90AA1 P07900 1/20 0.37
ESR2 Q92731 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9615543 0.93 ALDH1A1 (0.49) ALDH1A1EGLN1PGK1RHEBMAPT
SCHEMBL26790655 0.83 ALDH1A1 (0.49) ALDH1A1PGK1RHEBMAPTKDM4E
SCHEMBL12431605 0.80 MAPT (0.45) ALDH1A1MAPTKDM4EPOLBHPGD
SCHEMBL316047 0.80 ALDH1A1 (0.60) ALDH1A1RHEBMAPTKDM4EPOLB
SCHEMBL12020717 0.77 ALDH1A1 (0.56) ALDH1A1MAPTKDM4EPOLBHPGD
SCHEMBL17285610 0.76 HSP90AA1 (0.51) ALDH1A1EGLN1MAPTKDM4EPOLB
SCHEMBL24463172 0.74 ALDH1A1 (0.53) ALDH1A1RHEBMAPTKDM4EPOLB
SCHEMBL8265257 0.74 ALDH1A1 (0.53) ALDH1A1EGLN1MAPTKDM4EPOLB
SCHEMBL13041691 0.73 ALDH1A1 (0.59) ALDH1A1MAPTKDM4EPOLBHPGD
SCHEMBL8264566 0.73 ALDH1A1 (0.56) ALDH1A1MAPTKDM4EPOLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5115337-A Laser wavelength converter FUJI PHOTO FILM CO., LTD. (JP) 1992-05-19 US disclosed
US-4981613-A Laser light source FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US disclosed
US-4982112-A LASER WAVELENGTH CONVERSION FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US disclosed