Cyanide

Cyanide

SCHEMBL9616100

C#N.c1ccc([Sn](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
MGLL Q99685 1/20 0.32
TSHR P16473 4/20 0.32
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
CA12 O43570 1/20 0.30
GLA P06280 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA14 Q9ULX7 1/20 0.30
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29858810 0.89 ALDH1A1 (0.40) ALDH1A1MGLLTSHRCA1CA2
SCHEMBL124009 0.89 ALDH1A1 (0.40) ALDH1A1MGLLTSHRCA1CA2
Bromide SCHEMBL1029052 0.86 ALDH1A1 (0.38) ALDH1A1MGLLTSHRCA1CA2
Fluoride SCHEMBL1032387 0.86 ALDH1A1 (0.38) ALDH1A1MGLLTSHRCA1CA2
Water SCHEMBL247519 0.86 ALDH1A1 (0.38) ALDH1A1MGLLTSHRCA1CA2
SCHEMBL414674 0.86 ALDH1A1 (0.38) ALDH1A1MGLLTSHRCA1CA2
Hydrochloric Acid SCHEMBL153662 0.86 ALDH1A1 (0.38) ALDH1A1MGLLTSHRCA1CA2
Iodide SCHEMBL1030211 0.86 ALDH1A1 (0.38) ALDH1A1MGLLTSHRCA1CA2
SCHEMBL9064903 0.86 ALDH1A1 (0.38) ALDH1A1MGLLTSHRCA1CA2
SCHEMBL10938098 0.86 ALDH1A1 (0.38) ALDH1A1MGLLTSHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0510689-A1 Hydrocyanation of pentenenitriles using cyanohydrins E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-28 EP claimed
US-5107012-A Using an additive to promote dissociation of the cyanohydrin, a nickel complex catalyst and catalyst promoter; slurrying E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-21 US claimed