Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309325 | 0.92 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9309706 | 0.92 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL3473992 | 0.91 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9309781 | 0.91 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9309051 | 0.91 | AGTR1 (0.39) | AGTR1AGTR2 | |
| Water SCHEMBL9311609 | 0.91 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9309007 | 0.90 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9309653 | 0.89 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9309139 | 0.88 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9309539 | 0.87 | AGTR1 (0.36) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514192-A1 | Antihypertensive benzofuran derivatives, substituted by varied N-pyrimidinyl- or N-imidazolyl-methyl groups | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |