Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9616626 | 0.81 | AGTR1 (0.38) | AGTR1 | |
| SCHEMBL9616625 | 0.81 | AGTR1 (0.38) | AGTR1 | |
| SCHEMBL9467980 | 0.76 | AGTR1 (0.36) | AGTR1 | |
| SCHEMBL9468494 | 0.73 | AGTR1 (0.36) | AGTR1 | |
| SCHEMBL9616359 | 0.73 | AGTR1 (0.36) | AGTR1 | |
| SCHEMBL9309675 | 0.72 | AGTR1 (0.40) | AGTR1 | |
| SCHEMBL9860204 | 0.71 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL9468600 | 0.71 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL9694922 | 0.71 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL9309861 | 0.70 | AGTR1 (0.46) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514192-A1 | Antihypertensive benzofuran derivatives, substituted by varied N-pyrimidinyl- or N-imidazolyl-methyl groups | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |