Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127304 | 1.00 | TDP1 (0.52) | TDP1ALOX15SMN1; SMN2LMNAMMP1 | |
| SCHEMBL17402240 | 0.81 | TDP1 (0.45) | TDP1ALOX15SMN1; SMN2LMNAMMP1 | |
| SCHEMBL6433800 | 0.78 | TDP1 (0.56) | TDP1ALOX15SMN1; SMN2LMNAMMP1 | |
| SCHEMBL21456762 | 0.78 | TDP1 (0.50) | TDP1SMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL255602 | 0.77 | TSHR (0.50) | TDP1ALOX15SMN1; SMN2LMNAMMP1 | |
| SCHEMBL1442538 | 0.77 | TSHR (0.50) | TDP1ALOX15SMN1; SMN2LMNAMMP1 | |
| SCHEMBL7092944 | 0.77 | TSHR (0.50) | TDP1ALOX15SMN1; SMN2LMNAMMP1 | |
| SCHEMBL13849512 | 0.77 | TSHR (0.50) | TDP1ALOX15SMN1; SMN2LMNAMMP1 | |
| SCHEMBL42203 | 0.77 | TSHR (0.50) | TDP1ALOX15SMN1; SMN2LMNAMMP1 | |
| SCHEMBL9995363 | 0.76 | TDP1 (0.48) | TDP1SMN1; SMN2LMNAMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4001117-A | — | — | None | — | — | JP | disclosed |
| JP-H041117-A | COATING COSMETIC AND METHOD FOR FORMING MULTIPLE MAKEUP FILM | POLA CHEM IND INC | 1992-01-06 | — | — | JP | disclosed |