Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24241213 | 0.76 | MAPT (0.61) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10763870 | 0.76 | MAPT (0.61) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28418585 | 0.76 | MAPT (0.47) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13246749 | 0.71 | MAPT (0.65) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15942164 | 0.71 | MAPT (0.55) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9585181 | 0.70 | MAPT (0.39) | MAPTALDH1A1TDP1HTTKDM4E | |
| SCHEMBL27609999 | 0.70 | — | — | |
| Propane SCHEMBL9501767 | 0.67 | MAPT (0.54) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2599459 | 0.67 | — | — | |
| SCHEMBL28745188 | 0.67 | MAPT (0.48) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4202154-A | — | — | None | — | — | JP | disclosed |
| JP-H04202154-A | CHLOROALLYLHYDROXYCYCLOPENTENONE DERIVATIVE AND ITS PRODUCTION | SUMITOMO CHEM CO LTD | 1992-07-22 | — | — | JP | disclosed |